PUBLICATIONS
Ambrogi M, Hernandez LL, Strand DW, Kumar S, Romero MF, Barasch J, Ridlon M, Keil Stietz KP, Vezina CM. A 5-HT-mediated urethral defense against urinary tract infections. Proc Natl Acad Sci U S A. 2025 Apr 22;122(16):e2409754122. doi: 10.1073/pnas.2409754122. Epub 2025 Apr 14. PMID: 40228121.
Field SL, Arendt LM, Hernandez LL, Laporta J. Characterizing serotonin expression throughout bovine mammary gland developmental stages and its relationship with 17β-estradiol at puberty. PLoS One. 2025 Mar 25;20(3):e0319914. doi: 10.1371/journal.pone.0319914. PMID: 40131888; PMCID: PMC11936267.
Domingues RR, Wiltbank MC, Hernandez LL, Adcock SJJ. Prenatal treatment with the antidepressant fluoxetine on maternal and neonatal behavior in sheep. Pediatr Res. 2025 Jan 14. doi: 10.1038/s41390-025-03799-3. Epub ahead of print. PMID: 39809853.
Webster HH, Vang AL, Frizzarini WS, Cunha TO, Fricke HP, Moen ST, League LM, Lewandowski LR, Hernandez LL. Comparing the efficacy of serotonin and ethylene glycol tetraacetate on postpartum hypocalcemia. J Dairy Sci. 2025 Mar;108(3):2964-2980. doi: 10.3168/jds.2024-25338. Epub 2025 Jan 7. PMID: 39788187.
Frizzarini WS, Campolina JP, Connelly MK, Fricke HP, Hernandez LL. Effects of induced subclinical hypocalcemia in early-lactation Holstein cows without milking during infusion on parathyroid hormone and serotonin concentrations. JDS Commun. 2024 Jun 13;5(6):729-734. doi: 10.3168/jdsc.2024-0589. PMID: 39650027; PMCID: PMC11624329.
Vang AL, Bresolin T, Frizzarini WS, Campolina JP, Menezes GL, Rosa GJM, Dorea JRR, Hernandez LL. Monitoring mammary gland development in preweaning dairy heifers using ultrasound imaging. JDS Commun. 2024 May 31;5(6):725-728. doi: 10.3168/jdsc.2024-0586. PMID: 39650009; PMCID: PMC11624348.
Connelly MK, Rodney RM, Kuehnl J, Andrade JPN, Sonnewend Andrade F, Henschel S, Block E, Lean IJ, Hernandez LL. The effects of magnitude of calcium decline at the onset of lactation on serotonin dynamics and the serotonin-calcium axis. J Dairy Sci. 2025 Feb;108(2):1992-2004. doi: 10.3168/jds.2024-24836. Epub 2024 Oct 29. PMID: 39477066.
Vang AL, Dorea JRR, Hernandez LL. Graduate Student Literature Review: Mammary gland development in dairy cattle-Quantifying growth and development. J Dairy Sci. 2024 Dec;107(12):11611-11620. doi: 10.3168/jds.2024-25007. Epub 2024 Sep 28. PMID: 39343206; PMCID: PMC11614682.
Vang AL, Frizzarini WS, Webster HH, Cunha TO, Nelson KM, Dorea JRR, Hernandez LL. Ultrasound-assisted minimally invasive technique for tissue collection from bovine mammary glands. Vet Med Sci. 2024 Nov;10(6):e70027. doi: 10.1002/vms3.70027. PMID: 39294888; PMCID: PMC11410675.
Monteiro PLJ, Wiltbank MC, Frizzarini WS, Andrade JPN, Cabrera EM, Schoenfeld SG, Domingues RR, Hernandez LL. Hormonal profiles and biomarkers leading to parturition in cattle. Biol Reprod. 2024 Dec 12;111(6):1282-1296. doi: 10.1093/biolre/ioae133. PMID: 39221747.
McNeil BK, Renaud DL, Steele MA, Cangiano LR, Olmeda MF, Villot C, Chevaux E, Yu J, Hernandez LL, Frizzarini WS, DeVries TJ. Effects of weaning and inactivated Lactobacillus helveticus supplementation on dairy calf behavioral and physiological indicators of affective state. J Dairy Sci. 2024 Dec;107(12):11363-11380. doi: 10.3168/jds.2023-24581. Epub 2024 Jul 26. PMID: 39067749.
Desorcy-Scherer K, Zuniga-Chaves I, Reisner MA, Suen G, Hernandez LL. Investigating the influence of perinatal fluoxetine exposure on murine gut microbial communities during pregnancy and lactation. Sci Rep. 2024 Jun 14;14(1):13762. doi: 10.1038/s41598-024-62224-7. PMID: 38877103; PMCID: PMC11178873.
Field SL, Galvan EA, Hernandez LL, Laporta J. Exploring the contribution of mammary-derived serotonin on liver and pancreas metabolism during lactation. PLoS One. 2024 Jun 5;19(6):e0304910. doi: 10.1371/journal.pone.0304910. PMID: 38837989; PMCID: PMC11152252.
Frizzarini WS, Monteiro PLJ, Campolina JP, Vang AL, Soudah O, Lewandowski LR, Connelly MK, Arriola Apelo SI, Hernandez LL. Mechanisms by which feeding synthetic zeolite A and dietary cation-anion difference diets affect mineral metabolism in multiparous Holstein cows: Part I. J Dairy Sci. 2024 Jul;107(7):5204-5221. doi: 10.3168/jds.2024-24056. Epub 2024 Mar 14. PMID: 38490548.
Frizzarini WS, Campolina JP, Vang AL, Lewandowski LR, Teixeira NN, Connelly MK, Monteiro PLJ, Hernandez LL. Mechanisms by which feeding synthetic zeolite A and dietary cation-anion difference diets affect feed intake, energy metabolism, and milk performance: Part II. J Dairy Sci. 2024 Jul;107(7):5222-5234. doi: 10.3168/jds.2024-24057. Epub 2024 Mar 14. PMID: 38490547.
Desorcy-Scherer K, Fricke HP, Hernandez LL. Selective serotonin reuptake inhibitors during pregnancy and lactation: A scoping review of effects on the maternal and infant gut microbiome. Dev Psychobiol. 2024 Jan;66(1):e22441. doi: 10.1002/dev.22441. PMID: 38131241; PMCID: PMC11017378.
Pszczolkowski VL, Connelly MK, Hoppman A, Benn AD, Laporta J, Hernandez LL, Arriola Apelo SI. Intravenous infusion of 5-hydroxytryptophan to mid-lactation Holstein cows transiently affects milk production and circulating amino acid concentrations. J Dairy Sci. 2024 May;107(5):3306-3318. doi: 10.3168/jds.2023-23934. Epub 2023 Dec 14. PMID: 38101740.
Novo LC, Poindexter MB, Rezende FM, Santos JEP, Nelson CD, Hernandez LL, Kirkpatrick BW, Peñagaricano F. Identification of genetic variants and individual genes associated with postpartum hypocalcemia in Holstein cows. Sci Rep. 2023 Dec 11;13(1):21900. doi: 10.1038/s41598-023-49496-1. PMID: 38082150; PMCID: PMC10713536.
Fricke HP, Krajco CJ, Perry MJ, Brettingen LJ, Wake LA, Charles JF, Hernandez LL. Fluoxetine treatment during the postpartal period may have short-term impacts on murine maternal skeletal physiology. Front Pharmacol. 2023 Nov 23;14:1244580. doi: 10.3389/fphar.2023.1244580. PMID: 38074149; PMCID: PMC10701399.
Domingues RR, Teixeira NN, Frizzarini WS, Beard AD, Connelly MK, Vang A, Wiltbank MC, Hernandez LL. The antidepressant fluoxetine (Prozac®) modulates serotonin signaling to alter maternal peripartum calcium homeostasis. Sci Rep. 2023 Dec 9;13(1):21832. doi: 10.1038/s41598-023-49253-4. PMID: 38071334; PMCID: PMC10710465.
Star KE, Lindsey K, Reese SM, Paulino L, Hernandez LL, Tynes I, Eiseman K, Tynes J. Reducing central line-associated bloodstream infection with a dedicated CLABSI prevention registered nurse role. Am J Infect Control. 2024 Jun;52(6):659-663. doi: 10.1016/j.ajic.2023.11.021. Epub 2023 Dec 6. PMID: 38061403.
Fricke HP, Krajco CJ, Perry MJ, Desorcy-Scherer KM, Wake LA, Charles JF, Hernandez LL. Developmental fluoxetine exposure affects adolescent and adult bone depending on the dose and period of exposure in mice. Physiol Rep. 2023 Dec;11(23):e15881. doi: 10.14814/phy2.15881. PMID: 38031314; PMCID: PMC10687345.
Fricke HP, Krajco CJ, Perry MJ, Reisner MA, Brettingen LJ, Wake LA, Charles JF, Hernandez LL. In utero, lactational, or peripartal fluoxetine administration has differential implications on the murine maternal skeleton. Physiol Rep. 2023 Oct;11(19):e15837. doi: 10.14814/phy2.15837. PMID: 37813559; PMCID: PMC10562136.
Connelly MK, Harris RMR, Kuehnl J, Andrade JPN, Andrade FS, Henschel S, Block E, Lean IJ, Hernandez LL. Influence of prepartum dietary cation-anion difference and the magnitude of calcium decline at the onset of lactation on mineral metabolism and physiological responses. J Dairy Sci. 2024 Feb;107(2):1228-1243. doi: 10.3168/jds.2023-23588. Epub 2023 Sep 26. PMID: 37769944.
Hernandez LL, McArt JAA. Perspective: Transient postparturient hypocalcemia-A lactation-induced phenomenon of high-producing dairy cows. J Dairy Sci. 2023 Dec;106(12):8177-8180. doi: 10.3168/jds.2023-23355. Epub 2023 Aug 23. PMID: 37641345.
Vang AL, Bresolin T, Frizzarini WS, Menezes GL, Cunha T, Rosa GJM, Hernandez LL, Dorea JRR. Longitudinal analysis of bovine mammary gland development. J Mammary Gland Biol Neoplasia. 2023 May 30;28(1):11. doi: 10.1007/s10911-023-09534-0. PMID: 37249685; PMCID: PMC10229473.
Domingues RR, Wiltbank MC, Hernandez LL. Maternal serotonin: implications for the use of selective serotonin reuptake inhibitors during gestation†. Biol Reprod. 2023 Jul 11;109(1):17-28. doi: 10.1093/biolre/ioad046. PMID: 37098165; PMCID: PMC10344603.
Fricke HP, Hernandez LL. The Serotonergic System and Bone Metabolism During Pregnancy and Lactation and the Implications of SSRI Use on the Maternal-Offspring Dyad. J Mammary Gland Biol Neoplasia. 2023 Apr 22;28(1):7. doi: 10.1007/s10911-023-09535-z. PMID: 37086330; PMCID: PMC10122632.
Field SL, Davidson BD, Hoerl AF, Dado-Senn B, Hernandez LL, Laporta J. Amplifying local serotonin signaling prior to dry-off hastens mammary gland involution and redevelopment in dairy cows. J Dairy Sci. 2023 May;106(5):3719-3733. doi: 10.3168/jds.2022-22424. Epub 2023 Mar 29. PMID: 37002143.
Chandler TL, Westhoff TA, LaPierre PA, Frizzarini W, Hernandez LL, Overton TR, Mann S. Eucalcemia during lipopolysaccharide challenge in postpartum dairy cows: II. Calcium dynamics. J Dairy Sci. 2023 May;106(5):3601-3614. doi: 10.3168/jds.2022-22775. Epub 2023 Mar 29. PMID: 37002137.
Pszczolkowski VL, Connelly MK, Beard AD, Benn AD, Laporta J, Hernandez LL, Arriola Apelo SI. Serotonin alters the response to a glucose challenge in lactating cows. J Endocrinol. 2023 May 2;257(3):e220280. doi: 10.1530/JOE-22-0280. PMID: 36951553.
Domingues RR, Wiltbank MC, Hernandez LL. The antidepressant fluoxetine (Prozac®) modulates estrogen signaling in the uterus and alters estrous cycles in mice. Mol Cell Endocrinol. 2023 Jan 1;559:111783. doi: 10.1016/j.mce.2022.111783. Epub 2022 Oct 2. PMID: 36198363; PMCID: PMC10038119.
Domingues RR, Beard AD, Connelly MK, Wiltbank MC, Hernandez LL. Fluoxetine-induced perinatal morbidity in a sheep model. Front Med (Lausanne). 2022 Aug 4;9:955560. doi: 10.3389/fmed.2022.955560. PMID: 35991651; PMCID: PMC9386076.
Domingues RR, Wiltbank MC, Hernandez LL. Pregnancy Complications and Neonatal Mortality in a Serotonin Transporter Null Mouse Model: Insight Into the Use of Selective Serotonin Reuptake Inhibitor During Pregnancy. Front Med (Lausanne). 2022 Mar 10;9:848581. doi: 10.3389/fmed.2022.848581. PMID: 35360732; PMCID: PMC8960382.
Sheftel CM, Liu L, Field SL, Weaver SR, Vezina CM, Peñagaricano F, Hernandez LL. Impact of Fluoxetine Treatment and Folic Acid Supplementation on the Mammary Gland Transcriptome During Peak Lactation. Front Pharmacol. 2022 Feb 23;13:828735. doi: 10.3389/fphar.2022.828735. PMID: 35281892; PMCID: PMC8904566.
Field SL, Ouellet V, Sheftel CM, Hernandez LL, Laporta J. In vitro effects of 5-Hydroxy-L-tryptophan supplementation on primary bovine mammary epithelial cell gene expression under thermoneutral or heat shock conditions. Sci Rep. 2022 Mar 9;12(1):3820. doi: 10.1038/s41598-022-07682-7. PMID: 35264606; PMCID: PMC8907223.
Sheftel CM, Sartori LC, Hunt ER, Manuel RSJ, Bell AM, Domingues RR, Wake LA, Scharpf BR, Vezina CM, Charles JF, Hernandez LL. Peripartal treatment with low-dose sertraline accelerates mammary gland involution and has minimal effects on maternal and offspring bone. Physiol Rep. 2022 Mar;10(5):e15204. doi: 10.14814/phy2.15204. PMID: 35234346; PMCID: PMC8889862.
Domingues RR, Fricke HP, Sheftel CM, Bell AM, Sartori LC, Manuel RSJ, Krajco CJ, Wiltbank MC, Hernandez LL. Effect of Low and High Doses of Two Selective Serotonin Reuptake Inhibitors on Pregnancy Outcomes and Neonatal Mortality. Toxics. 2022 Jan 1;10(1):11. doi: 10.3390/toxics10010011. PMID: 35051053; PMCID: PMC8780128.
Connelly MK, Henschel SR, Kuehnl JM, Cheng AA, Nashold F, Hernandez LL. Physiological adaptations in early-lactation cows result in differential responses to calcium perturbation relative to nonlactating, nonpregnant cows. J Dairy Sci. 2022 Jan;105(1):904-920. doi: 10.3168/jds.2021-20890. Epub 2021 Oct 23. PMID: 34696912.
Connelly MK, Cheng AA, Hernandez LL. Graduate Student Literature Review: Serotonin and calcium metabolism: A story unfolding. J Dairy Sci. 2021 Dec;104(12):13008-13019. doi: 10.3168/jds.2021-20610. Epub 2021 Sep 14. PMID: 34531048.
Cheng AA, Li W, Hernandez LL. Investigating the effect of positional variation on mid-lactation mammary gland transcriptomics in mice fed either a low-fat or high-fat diet. PLoS One. 2021 Aug 26;16(8):e0255770. doi: 10.1371/journal.pone.0255770. PMID: 34437559; PMCID: PMC8389404.
Turco AE, Oakes SR, Keil Stietz KP, Dunham CL, Joseph DB, Chathurvedula TS, Girardi NM, Schneider AJ, Gawdzik J, Sheftel CM, Wang P, Wang Z, Bjorling DE, Ricke WA, Tang W, Hernandez LL, Keast JR, Bonev AD, Grimes MD, Strand DW, Tykocki NR, Tanguay RL, Peterson RE, Vezina CM. A mechanism linking perinatal 2,3,7,8 tetrachlorodibenzo-p-dioxin exposure to lower urinary tract dysfunction in adulthood. Dis Model Mech. 2021 Jul 1;14(7):dmm049068. doi: 10.1242/dmm.049068. Epub 2021 Jul 27. PMID: 34318329; PMCID: PMC8326766.
Cheng AA, Li W, Walker TM, Silvers C, Arendt LM, Hernandez LL. Investigating the complex interplay between genotype and high-fat-diet feeding in the lactating mammary gland using the Tph1 and Ldlr knockout models. Am J Physiol Endocrinol Metab. 2021 Mar 1;320(3):E438-E452. doi: 10.1152/ajpendo.00456.2020. Epub 2021 Jan 11. PMID: 33427054; PMCID: PMC7988787.
Sheftel CM, Hernandez LL. Serotonin stimulated parathyroid hormone related protein induction in the mammary epithelia by transglutaminase-dependent serotonylation. PLoS One. 2020 Oct 23;15(10):e0241192. doi: 10.1371/journal.pone.0241192. PMID: 33095824; PMCID: PMC7584195.
Connelly MK, Marshall AM, Crump PM, Hernandez LL. Short communication: The effect of ruminal administration of 5-hydroxy-l-tryptophan on circulating serotonin concentrations. J Dairy Sci. 2020 Nov;103(11):10850-10855. doi: 10.3168/jds.2019-18132. Epub 2020 Sep 18. PMID: 32952021.
Kuehnl JM, Connelly MK, Dzidic A, Lauber M, Fricke HP, Klister M, Olstad E, Balbach M, Timlin E, Pszczolkowski V, Crump PM, Reinemann DJ, Hernandez LL. Corrigendum: The effects of incomplete milking and increased milking frequency on milk production rate and milk composition. J Anim Sci. 2020 Mar 1;98(3):skaa061. doi: 10.1093/jas/skaa061. Erratum for: J Anim Sci. 2019 May 30;97(6):2424-2432. doi: 10.1093/jas/skz113. PMID: 32176781; PMCID: PMC7075661.
Wilkens MR, Nelson CD, Hernandez LL, McArt JAA. Symposium review: Transition cow calcium homeostasis-Health effects of hypocalcemia and strategies for prevention. J Dairy Sci. 2020 Mar;103(3):2909-2927. doi: 10.3168/jds.2019-17268. Epub 2020 Jan 15. PMID: 31954573.
Cheng AA, Li W, Hernandez LL. Transcriptomic analysis investigating the interaction between peripheral serotonin and high-fat diet feeding on mammary gene expression in midlactation mice. Physiol Genomics. 2020 Jan 1;52(1):47-55. doi: 10.1152/physiolgenomics.00073.2019. Epub 2019 Dec 9. PMID: 31814535.
Deer EM, Welch B, Hernandez LL, Seeley RJ, Grayson BE. Nutrient and hormone composition of milk is altered in rodent dams post-bariatric surgery. J Dev Orig Health Dis. 2020 Feb;11(1):71-77. doi: 10.1017/S2040174419000424. Epub 2019 Aug 9. PMID: 31397254; PMCID: PMC6934892.
Hernández-Castellano LE, Hernandez LL, Bruckmaier RM. Review: Endocrine pathways to regulate calcium homeostasis around parturition and the prevention of hypocalcemia in periparturient dairy cows. Animal. 2020 Feb;14(2):330-338. doi: 10.1017/S1751731119001605. Epub 2019 Jul 24. PMID: 31337460.
Zhang X, Wang X, Yin H, Zhang L, Feng A, Zhang QX, Lin Y, Bao B, Hernandez LL, Shi GP, Liu J. Functional Inactivation of Mast Cells Enhances Subcutaneous Adipose Tissue Browning in Mice. Cell Rep. 2019 Jul 16;28(3):792-803.e4. doi: 10.1016/j.celrep.2019.06.044. PMID: 31315055; PMCID: PMC6662660.
Carvalho PD, Santos VG, Fricke HP, Hernandez LL, Fricke PM. Effect of manipulating progesterone before timed artificial insemination on reproductive and endocrine outcomes in high-producing multiparous Holstein cows. J Dairy Sci. 2019 Aug;102(8):7509-7521. doi: 10.3168/jds.2019-16536. Epub 2019 May 31. PMID: 31155251.
Kuehnl JM, Connelly MK, Dzidic A, Lauber M, Fricker HP, Klister M, Olstad E, Balbach M, Timlin E, Pszczolkowski V, Crump PM, Reinemann DJ, Hernandez LL. The effects of incomplete milking and increased milking frequency on milk production rate and milk composition1. J Anim Sci. 2019 May 30;97(6):2424-2432. doi: 10.1093/jas/skz113. Erratum in: J Anim Sci. 2020 Mar 1;98(3):skaa061. doi: 10.1093/jas/skaa061. PMID: 30982896; PMCID: PMC6541812.
Niles AM, Fricke HP, Carvalho PD, Wiltbank MC, Hernandez LL, Fricke PM. Effect of treatment with human chorionic gonadotropin 7 days after artificial insemination or at the time of embryo transfer on reproductive outcomes in nulliparous Holstein heifers. J Dairy Sci. 2019 Mar;102(3):2593-2606. doi: 10.3168/jds.2018-15588. Epub 2019 Jan 26. PMID: 30692012.
Weaver SR, Xie C, Charles JF, Hernandez LL. In utero and lactational exposure to the Selective Serotonin Reuptake Inhibitor fluoxetine compromises pup bones at weaning. Sci Rep. 2019 Jan 18;9(1):238. doi: 10.1038/s41598-018-36497-8. PMID: 30659249; PMCID: PMC6338725.
Kessler EC, Wall SK, Hernandez LL, Gross JJ, Bruckmaier RM. Short communication: Mammary gland tight junction permeability after parturition is greater in dairy cows with elevated circulating serotonin concentrations. J Dairy Sci. 2019 Feb;102(2):1768-1774. doi: 10.3168/jds.2018-15543. Epub 2018 Dec 20. PMID: 30580948.
Metzger SA, Hernandez LL, Skarlupka JH, Walker TM, Suen G, Ruegg PL. A Cohort Study of the Milk Microbiota of Healthy and Inflamed Bovine Mammary Glands From Dryoff Through 150 Days in Milk. Front Vet Sci. 2018 Oct 9;5:247. doi: 10.3389/fvets.2018.00247. PMID: 30356776; PMCID: PMC6189514.
Weaver SR, Fricke HP, Xie C, Aiello RJ, Charles JF, Hernandez LL. Peripartum dietary supplementation of a small-molecule inhibitor of tryptophan hydroxylase 1 compromises infant, but not maternal, bone. Am J Physiol Endocrinol Metab. 2018 Dec 1;315(6):E1133-E1142. doi: 10.1152/ajpendo.00198.2018. Epub 2018 Oct 23. PMID: 30351987; PMCID: PMC6336963.
Cheng AA, Li W, Hernandez LL. Effect of high-fat diet feeding and associated transcriptome changes in the peak lactation mammary gland in C57BL/6 dams. Physiol Genomics. 2018 Dec 1;50(12):1059-1070. doi: 10.1152/physiolgenomics.00052.2018. Epub 2018 Oct 19. PMID: 30339477.
Amundson LA, Rowson AD, Crump PM, Prichard AP, Cheng AA, Wimmler CE, Klister M, Weaver SR, Bascom SS, Nuzback DE, Zanzalari KP, Hernandez LL. Effect of induced hypocalcemia in nonlactating, nonpregnant Holstein cows fed negative DCAD with low, medium, or high concentrations of calcium. J Anim Sci. 2018 Dec 3;96(12):5010-5023. doi: 10.1093/jas/sky371. PMID: 30321366; PMCID: PMC6276567.
Metzger SA, Hernandez LL, Suen G, Ruegg PL. Understanding the Milk Microbiota. Vet Clin North Am Food Anim Pract. 2018 Nov;34(3):427-438. doi: 10.1016/j.cvfa.2018.06.003. PMID: 30316501.
Kessler EC, Wall SK, Hernandez LL, Bruckmaier RM, Gross JJ. Short communication: Circulating serotonin is related to the metabolic status and lactational performance at the onset of lactation in dairy cows. J Dairy Sci. 2018 Dec;101(12):11455-11460. doi: 10.3168/jds.2018-14626. Epub 2018 Sep 20. PMID: 30243629.
Amundson LA, Hernandez LL, Crenshaw TD. Gene expression of matrix metalloproteinase 9 (MMP9), matrix metalloproteinase 13 (MMP13), vascular endothelial growth factor (VEGF) and fibroblast growth factor 23 (FGF23) in femur and vertebra tissues of the hypovitaminosis D kyphotic pig model. Br J Nutr. 2018 Aug;120(4):404-414. doi: 10.1017/S0007114518001605. Epub 2018 Jul 11. PMID: 29991364.
Weaver SR, Fricke HP, Xie C, Lipinski RJ, Vezina CM, Charles JF, Hernandez LL. Peripartum Fluoxetine Reduces Maternal Trabecular Bone After Weaning and Elevates Mammary Gland Serotonin and PTHrP. Endocrinology. 2018 Aug 1;159(8):2850-2862. doi: 10.1210/en.2018-00279. PMID: 29893816; PMCID: PMC6456925.
Penry JF, Crump PM, Hernandez LL, Reinemann DJ. Association of quarter milking measurements and cow-level factors in an automatic milking system. J Dairy Sci. 2018 Aug;101(8):7551-7562. doi: 10.3168/jds.2017-14153. Epub 2018 May 10. PMID: 29753475.
Hernandez LL. ADSA Foundation Scholar Award: A role for serotonin in lactation physiology-Where do we go from here? J Dairy Sci. 2018 Jul;101(7):5671-5678. doi: 10.3168/jds.2018-14562. Epub 2018 Apr 26. PMID: 29705428.
Metzger SA, Hernandez LL, Skarlupka JH, Suen G, Walker TM, Ruegg PL. Influence of sampling technique and bedding type on the milk microbiota: Results of a pilot study. J Dairy Sci. 2018 Jul;101(7):6346-6356. doi: 10.3168/jds.2017-14212. Epub 2018 Apr 19. PMID: 29680645.
Slater CJ, Endres EL, Weaver SR, Cheng AA, Lauber MR, Endres SF, Olstad E, DeBruin A, Crump PM, Block E, Hernandez LL. Interaction of 5-hydroxy-l-tryptophan and negative dietary cation-anion difference on calcium homeostasis in multiparous peripartum dairy cows. J Dairy Sci. 2018 Jun;101(6):5486-5501. doi: 10.3168/jds.2017-13938. Epub 2018 Mar 28. PMID: 29605319.
Weaver SR, Hernandez LL. Could use of Selective Serotonin Reuptake Inhibitors During Lactation Cause Persistent Effects on Maternal Bone? J Mammary Gland Biol Neoplasia. 2018 Jun;23(1-2):5-25. doi: 10.1007/s10911-018-9390-6. Epub 2018 Mar 30. PMID: 29603039.
Hernandez LL. TRIENNIAL LACTATION SYMPOSIUM/BOLFA: Serotonin and the regulation of calcium transport in dairy cows. J Anim Sci. 2017 Dec;95(12):5711-5719. doi: 10.2527/jas2017.1673. PMID: 29293773; PMCID: PMC6292306.
Martinez N, Rodney RM, Block E, Hernandez LL, Nelson CD, Lean IJ, Santos JEP. Effects of prepartum dietary cation-anion difference and source of vitamin D in dairy cows: Lactation performance and energy metabolism. J Dairy Sci. 2018 Mar;101(3):2544-2562. doi: 10.3168/jds.2017-13739. Epub 2017 Dec 21. PMID: 29274965.
Rodney RM, Martinez N, Block E, Hernandez LL, Celi P, Nelson CD, Santos JEP, Lean IJ. Effects of prepartum dietary cation-anion difference and source of vitamin D in dairy cows: Vitamin D, mineral, and bone metabolism. J Dairy Sci. 2018 Mar;101(3):2519-2543. doi: 10.3168/jds.2017-13737. Epub 2017 Dec 21. PMID: 29274979.
Penry JF, Crump PM, Hernandez LL, Reinemann DJ. Association of milking interval and milk production rate in an automatic milking system. J Dairy Sci. 2018 Feb;101(2):1616-1625. doi: 10.3168/jds.2016-12196. Epub 2017 Nov 15. PMID: 29153525.
Weaver SR, Jury NJ, Gregerson KA, Horseman ND, Hernandez LL. Characterization of mammary-specific disruptions for Tph1 and Lrp5 during murine lactation. Sci Rep. 2017 Nov 9;7(1):15155. doi: 10.1038/s41598-017-15508-0. PMID: 29123193; PMCID: PMC5680223.
Hernández-Castellano LE, Özçelik R, Hernandez LL, Bruckmaier RM. Short communication: Supplementation of colostrum and milk with 5-hydroxy-l-tryptophan affects immune factors but not growth performance in newborn calves. J Dairy Sci. 2018 Jan;101(1):794-800. doi: 10.3168/jds.2017-13501. Epub 2017 Nov 6. PMID: 29102139.
Weaver SR, Prichard AS, Maerz NL, Prichard AP, Endres EL, Hernández-Castellano LE, Akins MS, Bruckmaier RM, Hernandez LL. Elevating serotonin pre-partum alters the Holstein dairy cow hepatic adaptation to lactation. PLoS One. 2017 Sep 18;12(9):e0184939. doi: 10.1371/journal.pone.0184939. PMID: 28922379; PMCID: PMC5602632.
Amundson LA, Hernandez LL, Crenshaw TD. Serum and tissue 25-OH vitamin D3 concentrations do not predict bone abnormalities and molecular markers of vitamin D metabolism in the hypovitaminosis D kyphotic pig model. Br J Nutr. 2017 Jul;118(1):30-40. doi: 10.1017/S0007114517001751. Epub 2017 Jul 26. PMID: 28745259.
Hernández-Castellano LE, Hernandez LL, Sauerwein H, Bruckmaier RM. Endocrine and metabolic changes in transition dairy cows are affected by prepartum infusions of a serotonin precursor. J Dairy Sci. 2017 Jun;100(6):5050-5057. doi: 10.3168/jds.2016-12441. Epub 2017 Apr 21. PMID: 28434742.
Carvalho PD, Consentini CC, Weaver SR, Barleta RV, Hernandez LL, Fricke PM. Temporarily decreasing progesterone after timed artificial insemination decreased expression of interferon-tau stimulated gene 15 (ISG15) in blood leukocytes, serum pregnancy-specific protein B concentrations, and embryo size in lactating Holstein cows. J Dairy Sci. 2017 Apr;100(4):3233-3242. doi: 10.3168/jds.2016-11996. Epub 2017 Feb 8. PMID: 28189320.
Hernández-Castellano LE, Hernandez LL, Weaver S, Bruckmaier RM. Increased serum serotonin improves parturient calcium homeostasis in dairy cows. J Dairy Sci. 2017 Feb;100(2):1580-1587. doi: 10.3168/jds.2016-11638. Epub 2016 Dec 14. PMID: 27988124.
Penry JF, Endres EL, de Bruijn B, Kleinhans A, Crump PM, Reinemann DJ, Hernandez LL. Effect of incomplete milking on milk production rate and composition with 2 daily milkings. J Dairy Sci. 2017 Feb;100(2):1535-1540. doi: 10.3168/jds.2016-11935. Epub 2016 Dec 9. PMID: 27939533.
Weaver SR, Bohrer JC, Prichard AS, Perez PK, Streckenbach LJ, Olson JM, Cook ME, Hernandez LL. Serotonin Deficiency Rescues Lactation on Day 1 in Mice Fed a High Fat Diet. PLoS One. 2016 Sep 7;11(9):e0162432. doi: 10.1371/journal.pone.0162432. PMID: 27603698; PMCID: PMC5014414.
Amundson LA, Hernandez LL, Laporta J, Crenshaw TD. Maternal dietary vitamin D carry-over alters offspring growth, skeletal mineralisation and tissue mRNA expressions of genes related to vitamin D, calcium and phosphorus homoeostasis in swine. Br J Nutr. 2016 Sep;116(5):774-87. doi: 10.1017/S0007114516002658. Epub 2016 Aug 2. PMID: 27480125.
Weaver SR, Prichard AP, Endres EL, Newhouse SA, Peters TL, Crump PM, Akins MS, Crenshaw TD, Bruckmaier RM, Hernandez LL. Elevation of circulating serotonin improves calcium dynamics in the peripartum dairy cow. J Endocrinol. 2016 Jul;230(1):105-23. doi: 10.1530/JOE-16-0038. PMID: 27390301.
Weaver SR, Laporta J, Moore SA, Hernandez LL. Serotonin and calcium homeostasis during the transition period. Domest Anim Endocrinol. 2016 Jul;56 Suppl:S147-54. doi: 10.1016/j.domaniend.2015.11.004. PMID: 27345312.
Weaver SR, Cronick CM, Prichard AP, Laporta J, Benevenga NJ, Hernandez LL. Use of the RatLoft decreases pup mortality in lactating mice. Lab Anim. 2016 Oct;50(5):370-8. doi: 10.1177/0023677215617388. Epub 2015 Nov 14. PMID: 26568578.
Laporta J, Peñagaricano F, Hernandez LL. Transcriptomic Analysis of the Mouse Mammary Gland Reveals New Insights for the Role of Serotonin in Lactation. PLoS One. 2015 Oct 15;10(10):e0140425. doi: 10.1371/journal.pone.0140425. PMID: 26470019; PMCID: PMC4607441.
Weaver SR, Hernandez LL. Autocrine-paracrine regulation of the mammary gland. J Dairy Sci. 2016 Jan;99(1):842-53. doi: 10.3168/jds.2015-9828. Epub 2015 Aug 20. PMID: 26299162.
Keil KP, Altmann HM, Abler LL, Hernandez LL, Vezina CM. Histone acetylation regulates prostate ductal morphogenesis through a bone morphogenetic protein-dependent mechanism. Dev Dyn. 2015 Nov;244(11):1404-14. doi: 10.1002/dvdy.24321. Epub 2015 Sep 2. PMID: 26283270; PMCID: PMC4619142.
Laporta J, Moore SA, Weaver SR, Cronick CM, Olsen M, Prichard AP, Schnell BP, Crenshaw TD, Peñagaricano F, Bruckmaier RM, Hernandez LL. Increasing serotonin concentrations alter calcium and energy metabolism in dairy cows. J Endocrinol. 2015 Jul;226(1):43-55. doi: 10.1530/JOE-14-0693. PMID: 26099356.
Moore SA, Laporta J, Crenshaw TD, Hernandez LL. Patterns of circulating serotonin and related metabolites in multiparous dairy cows in the peripartum period. J Dairy Sci. 2015 Jun;98(6):3754-65. doi: 10.3168/jds.2014-8841. Epub 2015 Mar 28. PMID: 25828664.
Pai VP, Hernandez LL, Stull MA, Horseman ND. The type 7 serotonin receptor, 5-HT 7 , is essential in the mammary gland for regulation of mammary epithelial structure and function. Biomed Res Int. 2015;2015:364746. doi: 10.1155/2015/364746. Epub 2015 Jan 18. PMID: 25664318; PMCID: PMC4312625.
Laporta J, Hernandez LL. Serotonin receptor expression is dynamic in the liver during the transition period in Holstein dairy cows. Domest Anim Endocrinol. 2015 Apr;51:65-73. doi: 10.1016/j.domaniend.2014.11.005. Epub 2014 Nov 26. PMID: 25528206.
Laporta J, Keil KP, Weaver SR, Cronick CM, Prichard AP, Crenshaw TD, Heyne GW, Vezina CM, Lipinski RJ, Hernandez LL. Serotonin regulates calcium homeostasis in lactation by epigenetic activation of hedgehog signaling. Mol Endocrinol. 2014 Nov;28(11):1866-74. doi: 10.1210/me.2014-1204. Epub 2014 Sep 5. PMID: 25192038; PMCID: PMC4213360.
Laporta J, Gross JJ, Crenshaw TD, Bruckmaier RM, Hernandez LL. Short communication: Timing of first milking affects serotonin (5-HT) concentrations. J Dairy Sci. 2014 May;97(5):2944-8. doi: 10.3168/jds.2013-7336. Epub 2014 Mar 5. PMID: 24612806.
Keil KP, Abler LL, Mehta V, Altmann HM, Laporta J, Plisch EH, Suresh M, Hernandez LL, Vezina CM. DNA methylation of E-cadherin is a priming mechanism for prostate development. Dev Biol. 2014 Mar 15;387(2):142-53. doi: 10.1016/j.ydbio.2014.01.020. Epub 2014 Feb 3. PMID: 24503032; PMCID: PMC3976955.
Marshall AM, Hernandez LL, Horseman ND. Serotonin and serotonin transport in the regulation of lactation. J Mammary Gland Biol Neoplasia. 2014 Mar;19(1):139-46. doi: 10.1007/s10911-013-9304-6. Epub 2013 Oct 18. PMID: 24136337.
Horseman ND, Hernandez LL. New concepts of breast cell communication to bone. Trends Endocrinol Metab. 2014 Jan;25(1):34-41. doi: 10.1016/j.tem.2013.08.004. Epub 2013 Sep 18. PMID: 24055165.
Laporta J, Moore SA, Peters MW, Peters TL, Hernandez LL. Short communication: Circulating serotonin (5-HT) concentrations on day 1 of lactation as a potential predictor of transition-related disorders. J Dairy Sci. 2013 Aug;96(8):5146-50. doi: 10.3168/jds.2013-6718. Epub 2013 Jun 5. PMID: 23746592.
Laporta J, Peters TL, Merriman KE, Vezina CM, Hernandez LL. Serotonin (5-HT) affects expression of liver metabolic enzymes and mammary gland glucose transporters during the transition from pregnancy to lactation. PLoS One. 2013;8(2):e57847. doi: 10.1371/journal.pone.0057847. Epub 2013 Feb 28. PMID: 23469086; PMCID: PMC3585179.
Collier RJ, Hernandez LL, Horseman ND. Serotonin as a homeostatic regulator of lactation. Domest Anim Endocrinol. 2012 Aug;43(2):161-70. doi: 10.1016/j.domaniend.2012.03.006. Epub 2012 Apr 19. PMID: 22608139.
Hernandez LL, Grayson BE, Yadav E, Seeley RJ, Horseman ND. High fat diet alters lactation outcomes: possible involvement of inflammatory and serotonergic pathways. PLoS One. 2012;7(3):e32598. doi: 10.1371/journal.pone.0032598. Epub 2012 Mar 5. PMID: 22403677; PMCID: PMC3293832.
Hernandez LL, Gregerson KA, Horseman ND. Mammary gland serotonin regulates parathyroid hormone-related protein and other bone-related signals. Am J Physiol Endocrinol Metab. 2012 Apr 15;302(8):E1009-15. doi: 10.1152/ajpendo.00666.2011. Epub 2012 Feb 7. PMID: 22318950; PMCID: PMC3774078.
Hernandez LL, Collier JL, Vomachka AJ, Collier RJ, Horseman ND. Suppression of lactation and acceleration of involution in the bovine mammary gland by a selective serotonin reuptake inhibitor. J Endocrinol. 2011 Apr;209(1):45-54. doi: 10.1530/JOE-10-0452. Epub 2011 Feb 9. PMID: 21307120.
Yates DT, Strosser GL, Black PL, Halalsheh RA, Lankford LM, Hernandez LL, Löest CA, Ross TT. Technical note: Effects of rumen passage on fluoxetine bioavailability in serum and effects of fluoxetine on serum prolactin concentration and demeanor in ewes. J Anim Sci. 2010 Nov;88(11):3611-6. doi: 10.2527/jas.2010-3076. Epub 2010 Jul 9. PMID: 20622183.
Marshall AM, Nommsen-Rivers LA, Hernandez LL, Dewey KG, Chantry CJ, Gregerson KA, Horseman ND. Serotonin transport and metabolism in the mammary gland modulates secretory activation and involution. J Clin Endocrinol Metab. 2010 Feb;95(2):837-46. doi: 10.1210/jc.2009-1575. Epub 2009 Dec 4. PMID: 19965920; PMCID: PMC2840848.
Pai VP, Marshall AM, Hernandez LL, Buckley AR, Horseman ND. Altered serotonin physiology in human breast cancers favors paradoxical growth and cell survival. Breast Cancer Res. 2009;11(6):R81. doi: 10.1186/bcr2448. Epub 2009 Nov 10. PMID: 19903352; PMCID: PMC2815543.
Hernandez LL, Limesand SW, Collier JL, Horseman ND, Collier RJ. The bovine mammary gland expresses multiple functional isoforms of serotonin receptors. J Endocrinol. 2009 Oct;203(1):123-31. doi: 10.1677/JOE-09-0187. Epub 2009 Aug 4. PMID: 19654143; PMCID: PMC2741409.
Hernandez LL, Stiening CM, Wheelock JB, Baumgard LH, Parkhurst AM, Collier RJ. Evaluation of serotonin as a feedback inhibitor of lactation in the bovine. J Dairy Sci. 2008 May;91(5):1834-44. doi: 10.3168/jds.2007-0766. PMID: 18420614.